A Yes, mostly on shallow queue random 4k operations, by up to around 40 MBps
CPU power saving states allow idle cores to sleep (C1) or partially sleep (C2...). Activating a core from a sleeping or partially sleeping state takes enough time to impact SSD performance by up to 40 MBps. The changes in performance are most noticeable on shallow queue depth random 4K operations. Even headline sequential speeds can be impacted by up to around 20 MB/s. For most users, disabling power saving states in the BIOS is not worth the slightly higher power consumption and reduced peak CPU performance that results. Peak CPU performance is reduced on Intel chips because of the way turbo boost is implemented. In order to turbo boost an active core, inactive cores are put to sleep in order to keep overall temperature down.

The Best.
CPUGPUSSD
Intel Core i7-7700K $297Nvidia GTX 1070 $410Samsung 850 Evo 250GB $97
AMD Ryzen 7 1700 $270AMD RX 480 $350Samsung 850 Pro 256GB $120
Intel Core i5-7600K $220Nvidia GTX 1060-6GB $265Samsung 850 Evo 500GB $149
HDDRAMUSB
Seagate Barracuda 1TB (2016) $45G.SKILL Trident Z DDR4 3200 C14 4x16GB $724SanDisk Extreme 64GB $33
Seagate Barracuda 3TB (2016) $77Corsair Vengeance LPX DDR4 3000 C15 2x8GB $152SanDisk Extreme 32GB $22
Seagate Barracuda 7200.14 1TB $40HyperX Fury DDR4 2133 C14 2x8GB $141SanDisk Extreme 16GB $20
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