A Yes, mostly on shallow queue random 4k operations, by up to around 40 MBps
CPU power saving states allow idle cores to sleep (C1) or partially sleep (C2...). Activating a core from a sleeping or partially sleeping state takes enough time to impact SSD performance by up to 40 MBps. The changes in performance are most noticeable on shallow queue depth random 4K operations. Even headline sequential speeds can be impacted by up to around 20 MB/s. For most users, disabling power saving states in the BIOS is not worth the slightly higher power consumption and reduced peak CPU performance that results. Peak CPU performance is reduced on Intel chips because of the way turbo boost is implemented. In order to turbo boost an active core, inactive cores are put to sleep in order to keep overall temperature down.

The Best.
CPUGPUSSD
Intel Core i5-9600K $218Nvidia GTX 1660S (Super) $240Crucial MX500 250GB $43
Intel Core i5-9400F $155Nvidia GTX 1650S (Super) $170Samsung 850 Evo 120GB $78
Intel Core i7-9700K $370Nvidia RTX 2060 $340Samsung 850 Pro 512GB $204
HDDRAMUSB
Seagate Barracuda 1TB (2016) $37Corsair Vengeance LPX DDR4 3200 C16 2x8GB $73SanDisk Extreme 64GB $72
WD Blue 1TB (2012) $42Corsair Vengeance LPX DDR4 3000 C15 2x8GB $63SanDisk Extreme 32GB $46
Seagate Barracuda 3TB (2016) $85G.SKILL Trident Z DDR4 3200 C14 4x16GB $643SanDisk Ultra Fit 32GB $16
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