A Yes, mostly on shallow queue random 4k operations.
CPU power saving states allow idle cores to sleep (C1) or partially sleep (C2...). Activating a core from a sleeping or partially sleeping state takes enough time to impact SSD performance by up to 100 MBps. The changes in performance are most noticeable on shallow queue depth random 4K operations. Even headline sequential speeds can be impacted. For most users, disabling power saving states in the BIOS is not worth the slightly higher power consumption and reduced peak CPU performance that results. Peak CPU performance is reduced on Intel chips because of the way turbo boost is implemented: in order to turbo boost an active core, inactive cores are put to sleep in order to keep overall temperature down.

The Best.
CPUGPUSSD
Intel Core i5-9400F $165Nvidia GTX 1660S (Super) $230Crucial MX500 250GB $49
Intel Core i5-9600K $199Nvidia GTX 1650S (Super) $160Samsung 850 Evo 120GB $78
Intel Core i7-9700K $365Nvidia RTX 2070S (Super) $500Samsung 850 Pro 512GB $240
HDDRAMUSB
Seagate Barracuda 1TB (2016) $43Corsair Vengeance LPX DDR4 3200 C16 2x8GB $80SanDisk Extreme 64GB $72
WD Blue 1TB (2012) $40Corsair Vengeance LPX DDR4 3000 C15 2x8GB $75SanDisk Extreme 32GB $46
Seagate Barracuda 3TB (2016) $85G.SKILL Trident Z DDR4 3200 C14 4x16GB $681SanDisk Ultra Fit 32GB $16
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